>>> Reboul Cyril

Contact

Structure(s) de rattachement

Rattachement(s) externe(s)

- Membre du comité Scientifique de l'association 3S (Bruxelles- Belgique)

- Membre du GRRC (Groupe de Reflexion sur la Recherche Cardiovasculaire)

- Membre de la société de Physiologie

- Expert pour le "Qatar National Research Fund"

Disciplines enseignées

- Biologie et physiologie Animale (Licence SVT)

- Sciences Biologiques, Neurophysiologie, Physiologie humaine  (Licence STAPS)

- Physiopathologie Cardiaque, cibles moléculaires (Master STAPS)

- Physiopathologie cardiovasculaire et pollution urbaine (Faculté de Médecine, Nîmes-Montpellier)

Thème(s) de recherche

Santé Cardiovasculaire et Exercice.

Lauréat de la bourse de recherche "coeur et sport" de la société Française de Cardiologie (financé par la société "Sanofi-Aventis france")

Implication du rôle de la voie métabolique de l'oxyde nitrique dans la cardioprotection induite par l'exercice. Rôle du CO dans le remodelage myocardique et la sensibilité du coeur à l'ischémie-reperfusion.

Mots clés : Ischémie reperfusion, exercice, cardiaque, NO, pathologie cardiométabolique, Monoxyde de carbone

Equipe(s) de recherche

EA 4278, Laboratoire de pharm-écologie cardiovasculaire

site du laboratoire : blogs.univ-avignon.fr/lapec/

Publications

Principales publications :

Carbon monoxide exposure enhances arrhythmia after cardiac stress: involvement of oxidative stress. André L, Gouzi F, Thireau J, Meyer G, Boissiere J, Delage M, Abdellaoui A, Feillet-Coudray C, Fouret G, Cristol JP, Lacampagne A, Obert P, Reboul C, Fauconnier J, Hayot M, Richard S, Cazorla O. Basic Res Cardiol. 2011 Aug 6. [Epub ahead of print]

Carbon monoxide pollution impairs myocardial perfusion reserve: Implication of coronary endothelial dysfunction; Meyer G, Boissiere J, Tanguy S, Rugale C, Gayrard S, Jover B, Obert P, Reboul C; Cardiovasc Toxicol 2011 In Press

Beta-Adrenergic receptors desensitization is not involved in exercise-induced cardiac fatigue: NADPHoxidase-induced oxidative stress as a new trigger; Vitiello D, Boissiere J, Doucende G, Gayrard S, Polge A, Faure P, Goux A, Tanguy S, Obert P, Reboul C, Nottin S; J. Appl. Physiol. 2011 In Press

Plasma volume and arterial stiffness in the cardiac alterations associated with long-term high sodium feeding in rats; Cordaillat M, Reboul C, Gaillard V, Lartaud I, Jover B, Rugale C.; Am J Hypertens. 2011 Jan 13. [Epub ahead of print] 2011

Moderate exercise prevents impaired Ca²⁺ handling in heart of CO exposed rat: implication for sensitivity to ischemia-reperfusion; C. Farah MSc, G. Meyer MSc, L. André MSc, J. Boissière PhD, S. Gayrard BSc, O. Cazorla PhD, S. Richard PhD, F. Boucher PhD, S. Tanguy PhD, P. Obert PhD, C. Reboul PhD; Am. J. Physiol. Heart Circ Physiol; 2010 Dec

Simulated urban carbon monoxide air pollution exacerbates rat heart ischemia reperfusion injury; G. Meyer, L. Andre, S. Tanguy, J. Boissiere, C. Farah, F. Lopez-Lauri, S. Gayrard, S. Richard, F. Boucher, O. Cazorla, P. Obert, C. Reboul; Am. J. Physiol. Heart Circ. Physiol. doi : 10.1152/ajpheart.01194.2009. 2010

Carbon monoxide pollution promotes cardiac remodelling and ventricular arrhythmia in healthy rats; L. Andre; J. Boissiere; C. Reboul; R. Perrier; S. Zalvidea; G. Meyer; J. Thireau; S. Tanguy; P. Bideaux; M. Hayot; F. Boucher; P. Obert; O. Cazorla; S. Richard; Am. J. Respir. Crit. Care Med. doi: 10.1164/rccm.200905-0794OC. 2010

Endothelium-dependent Vasodilator Dysfunction Consecutive to Chronic-Hypoxic Stress in the Rat Hindlimb Vasculature: NO and EDHF Involvement; C. Reboul, A. Gibault, S. Tanguy, M. Dauzat, P. Obert; Vascul Pharmacol. 51: 154-161 2009

Late exercise training normalizes cell function and improves left ventricular pump function in rats with heart failure; Y. Ait Mou, C. Reboul, L. Andre, A. Lacampagne, O. Cazorla; Cardiovascular Research 15;81(3):555-64. 2009

Aortic vasoconstriction related to smooth muscle cells ET-A and ET-B receptors is not involved in hypoxia-induced sustained systemic hypertension; C. Reboul, J. Barbier, L. Goret, B. Saïag, A. Gibault, M. Dauzat, P. Obert, S. Tanguy; Vascular Pharmacology; 47: 209-14, 2007  

Impairment in left ventricular filling consecutive to altitude training: alterations in preload conditions rather than intrinsic relaxation properties; C. Reboul, S. Tanguy, A. Melin, JM Juan, M. Dauzat, P. Obert; Sciences et sports; 22 : 73-77, 2007

Chronic exercise does not prevent hypoxia-induced increased aortic sensitivity to endothelin in rats; C. Reboul, S. Tanguy, M. Dauzat, P. Obert; Vascular Pharmacology ; May;44(5):333-7, 2006

Invited comment in a point-counterpoint debate: “Positive effects of intermittent hypoxia (living high: training low) on exercise performance are / are not mediated primarily by augmented red cell volume”; C. Reboul, S. Tanguy;  Journal of Applied Physiology; 100: 365-6, 2006

Cardiac remodeling and functional adaptations consecutive to altitude training in rats: Implications for sea level aerobic performances; C. Reboul, S. Tanguy, J.M. Juan, M. Dauzat, P. Obert.; Journal of Applied Physiology; 98: 83-92, 2005  

Altitude negates the benefits of training on the vascular adaptations in rats; C. Reboul, S. Tanguy, M. Dauzat, P; Obert; Medicine & Science in Sports & Exercise; 37(6):979-85, 2005  

Chronic hypoxia exposure depresses aortic endothelium-dependent vasorelaxation in both sedentary and trained rats: involvement of L-arginine; C. Reboul, S. Tanguy, A. Gibault, M. Dauzat, P. Obert;  Journal of Applied Physiology; 99(3):1029-35, 2005 

Training does not affect the alteration in pulmonary artery vasoreactivity in pulmonary hypertensive rats; L. Goret, C. Reboul, S. Tanguy, M. Dauzat, P. Obert; European Journal of Pharmacology; 527(1-3):121-8, 19 décembre 2005